Dr. Ridhima Bindlish<br />

Dr. Niharika Garach

Surgical Oncologist

Difference Between Endometrial and Cervical Cancer

Difference Between Endometrial and Cervical Cancer

Cancer can be a scary diagnosis and one that many women don’t know much about. When it comes to endometrial and cervical cancer, it is important to understand how these two types differ.

By understanding the differences between them, we are able to better equip ourselves with the knowledge needed to plan an effective treatment program that meets our individual needs.

In this blog post, we’ll explore endometrial and cervical cancers in further detail so you can become more informed on which type of cancer you may have.

Endometrial Cancer

Endometrial cancer is a type of cancer that begins in the uterus, specifically in the endometrium, which is the inner lining of the uterus. This lining plays a significant role in preparing the uterus for pregnancy and menstruating if pregnancy doesn’t occur.

Risk factors associated with endometrial cancer include obesity, hormone imbalances, and certain genetic factors. Symptoms may range from abnormal vaginal bleeding (especially postmenopause), and pelvic pain, to unexplained weight loss.

It’s essential to seek medical attention if you experience any persistent symptoms that worry you. Remember, early detection often leads to more effective treatment and better prognosis.

Cervical Cancer

Cervical cancer is a type of cancer that occurs in the cervix, the lower part of the uterus that connects to the vagina. The cervix plays an integral role in the female reproductive system, serving as a protective barrier and a passageway for menstrual blood and sperm.

The primary risk factor for cervical cancer is infection with high-risk types of human papillomavirus (HPV), a sexually transmitted infection. Other risk factors include smoking, a weakened immune system, and long-term use of oral contraceptives.

Regular cervical screening tests, also known as Pap smears, are crucial for early detection of precancerous changes in the cervix. The HPV vaccination can also prevent most cases of cervical cancer by protecting against the most common types of HPV.

In conclusion, understanding your body and the potential health risks associated with different parts of your reproductive system empowers you to take charge of your health. Regular check-ups and screenings are key to early detection and effective treatment of both endometrial and cervical cancer.

Understanding Endometrial and Cervical Cancer: Symptoms and Warning Signs

While both endometrial and cervical cancer occur in the female reproductive system, they have distinct symptoms that can serve as early warning signs. Recognizing these symptoms is crucial for early detection, which significantly improves treatment outcomes.

Endometrial Cancer Symptoms

Endometrial cancer primarily affects the inner lining of the uterus, known as the endometrium. The most common symptom of endometrial cancer is unusual vaginal bleeding, which could include spotting, bleeding between periods, or postmenopausal bleeding. Other symptoms may include:

  • Pelvic pain or discomfort
  • Unexplained weight loss


Cervical Cancer Symptoms

Cervical cancer occurs in the cervix, the lower part of the uterus that connects to the vagina. Early-stage cervical cancer generally produces no signs or symptoms, highlighting the importance of regular screening via Pap smears. Advanced-stage cervical cancer symptoms may include:

  • Abnormal vaginal bleeding, such as bleeding after sex, between periods, or after menopause
  • Unusual vaginal discharge, which may be watery, bloody, or have a foul odor
  • Pain during sex

It’s important to note that these symptoms can also be associated with conditions other than cancer. However, if you observe any of these signs persistently, it’s crucial to consult your best Endometrial cancer Surgeon in Mumbai promptly for evaluation.

In conclusion, being vigilant about any unusual changes in your body is a critical step towards proactive healthcare. Regular screenings and check-ups are key to early detection and effective treatment of both endometrial and cervical cancer.

Diagnosing Endometrial and Cervical Cancer:

Diagnosing endometrial and cervical cancers involves a series of steps, including physical examinations, imaging tests, biopsies, and other diagnostic procedures. Early diagnosis is crucial as it can significantly improve treatment outcomes.

Diagnosing Endometrial Cancer

The diagnostic process for endometrial cancer typically begins with a pelvic exam to check for any abnormal areas or lumps around the vagina, cervix, and uterus.

This may be followed by a transvaginal ultrasound, which uses sound waves to create images of the uterus, thus helping to identify any abnormalities.

A definitive diagnosis of endometrial cancer usually requires an endometrial tissue sample, obtained via curettage or biopsy[^3^]. In some cases, a hysteroscopy may be performed, where a thin, lighted tube is inserted into the vagina to examine the cervix and inside of the uterus.

While in other cases we may need to do a dilatation and curettage to get a tissue sample for diagnosis. Some patients can even be offered an office endometrial biopsy with a pipeline.

Imaging preferably with an MRI is the next important step. It helps us identify several features which facilitate our treatment planning.

Other tests that may be used to diagnose endometrial cancer include a complete blood count (CBC) and CA 125 test, which measures the amount of the protein CA 125 in the blood. Some types of endometrial cancer can cause a high level of CA 125.

Diagnosing Cervical Cancer

The process of diagnosing cervical cancer often starts with a Pap smear, a screening test that examines cells from the cervix to check for abnormalities.

If abnormal cells are detected, a procedure called a colposcopy may be performed to closely examine the cervix, vagina, and vulva for signs of disease.

If these tests suggest the presence of cervical cancer, a biopsy will likely be performed to confirm the diagnosis. During this procedure, a small piece of tissue is removed from the cervix and examined under a microscope.

Imaging preferably with an MRI before biopsy and after clinical examination greatly helps in planning management.

Early detection of both endometrial and cervical cancers is key to improving treatment outcomes. Regular screenings and reporting any unusual symptoms to your gynecologist can aid in early diagnosis.

Also, Read- Endometrial Cancer Risk Factors 

Treatment Options for Endometrial and Cervical Cancer

The treatment options for both endometrial and cervical cancer are diverse and depend largely on the stage and severity of the disease. The main treatment modalities include surgery, radiation therapy, chemotherapy, and in some cases, targeted therapy or immunotherapy.


For both endometrial and cervical cancer, surgery is often the primary treatment option. This typically involves the removal of the uterus (hysterectomy), and may also include removal of the ovaries and fallopian tubes. In more advanced cases, lymph nodes in the pelvic area might also be removed.

Radiation Therapy

Radiation therapy uses high-energy rays to kill cancer cells. It can be used before surgery to shrink tumors, or after surgery to kill any remaining cancer cells. Radiation can also be used as the main treatment for patients who cannot have surgery.


Chemotherapy uses drugs to destroy cancer cells throughout the body. It can be used to treat both endometrial and cervical cancer, especially if the cancer has spread beyond the uterus or cervix. Sometimes, chemotherapy is used in combination with radiation therapy.

The choice of treatment depends on several factors including the type and stage of the cancer, potential side effects, the patient’s overall health, and their preferences.

It’s important to note that treatment plans are often personalized and involve a multidisciplinary team of healthcare professionals including gynecologic oncologists, radiation oncologists, medical oncologists, and nurses.

In conclusion, while the diagnosis of endometrial or cervical cancer can be overwhelming, there are several treatment options available. Personalized treatment plans, regular follow-ups, and a supportive team can help improve outcomes and quality of life for patients.

Also, Read- Survival Rates for Endometrial Cancer

Expertise in Endometrial Cancer (uterine Cancer)Treatment

“Take control of your health and explore our comprehensive endometrial cancer treatment in Mumbai options at SSO Hospital. Schedule a consultation today. know more our expert endometrial Surgeon will guide you towards a brighter, cancer-free future.”


In this article, we’ve delved into the intricate world of endometrial and cervical health, focusing specifically on the cancers associated with these areas.

We’ve learned that endometrial cancer originates in the inner lining of the uterus, while cervical cancer starts in the lower part of the uterus that connects to the vagina.

Each of these cancers carries unique risk factors and symptoms. Endometrial cancer is often tied to obesity, hormone imbalances, and certain genetic factors, with abnormal vaginal bleeding being a common symptom.

On the other hand, the primary risk factor for cervical cancer is infection with high-risk types of human papillomavirus (HPV), and its symptoms can range from unusual vaginal discharge to pain during intercourse.

Early detection of both these cancers dramatically improves prognosis and treatment outcomes. 

It’s important to remember that communication with your physician is key. Never hesitate to discuss any concerns or symptoms you may have, and always actively participate in your treatment decisions. Knowledge is power, and understanding your body gives you the ability to make informed decisions about your health.

Finally, for those facing a diagnosis of endometrial or cervical cancer, remember that medical advancements are continually improving our ability to treat these conditions effectively.

There is hope, and you are not alone in this journey. Stay empowered, stay informed, and never lose sight of the strength within you.