Dr. Niharika Garach
MBBS, MS, MCh
What is an Endometrial Biopsy?

Welcome to the world of women’s health. In this article, we will explore the fascinating topic of endometrial biopsies.
Whether you’ve heard the term before or it’s completely new to you, we’re here to provide you with a comprehensive guide that will help you understand what an endometrial biopsy is all about.
What is The Purpose of Endometrial Biopsy
An endometrial biopsy is a medical procedure that involves obtaining a small sample of tissue from the lining of the uterus, called the endometrium.
This procedure is typically performed to investigate and diagnose various gynecological conditions.
The purpose of an endometrial biopsy is to gather information about the health of the uterus and to identify any abnormalities or potential issues.
Indications for the Procedure
There are several reasons why a physician may recommend an endometrial biopsy. Some common indications include:
- Abnormal uterine bleeding: If you are experiencing irregular, heavy, or prolonged menstrual bleeding, an endometrial biopsy may be recommended to determine the cause.
- Postmenopausal bleeding: Any bleeding that occurs after menopause should be evaluated, and an endometrial biopsy can help identify potential underlying causes.
- Monitoring hormone therapy: For women undergoing hormone therapy, an endometrial biopsy may be performed periodically to assess the effects of the treatment.
- Infertility investigation: If you are having difficulty getting pregnant, an endometrial biopsy may be part of the diagnostic process to evaluate the uterine lining.
- Suspected uterine abnormalities: If your gynecologist suspects the presence of uterine polyps, fibroids, or other structural abnormalities, an endometrial biopsy may be recommended.
It’s important to note that your physician will assess your specific situation and determine if an endometrial cancer biopsy is necessary based on your symptoms, medical history, and physical examination.
How It Is Performed
During an endometrial biopsy, the endometrial doctor will carefully collect a small sample of tissue from the lining of your uterus.
The procedure is typically performed in an office setting and usually takes only a few minutes.
You will be positioned on an examination table, similar to a pelvic exam. The doctor will insert a speculum into your vagina to visualize the cervix.
Then, a thin, flexible tube called a catheter will be gently inserted through the cervix into the uterus.
This catheter allows for the collection of the endometrial tissue sample. Some women may experience mild discomfort or cramping during the procedure, but it is generally well-tolerated.
Also, Read- Survival Rates for Endometrial Cancer
Types of Endometrial Biopsies
There are different techniques used to perform endometrial biopsies. The most common types include:
- Pipelle biopsy: This technique involves using a thin, straw-like device to gently suction a sample of the endometrial tissue.
- Hysteroscopy-guided biopsy: In some cases, a hysteroscope (a thin, lighted tube) may be used to visualize the inside of the uterus and guide the biopsy procedure.
- Dilation and curettage (D&C): Although less commonly used today, D&C involves dilating the cervix and scraping the uterine lining to obtain a tissue sample.
The physician will determine the most appropriate technique based on your specific circumstances and needs.
Expertise in Endometrial Cancer (uterine Cancer)Treatment
What Are The Risks of an Endometrial Biopsy?
Like any medical procedure, an endometrial biopsy carries a small risk of complications. However, serious complications are rare. Some potential risks include:
- Mild discomfort: It is common to experience cramping, similar to menstrual cramps, during and after the procedure. This discomfort usually subsides within a short period.
- Spotting or bleeding: Some women may experience light spotting or minimal bleeding after the biopsy. This is usually temporary and resolves on its own.
- Infection: Although rare, there is a small risk of infection associated with any procedure that involves entering the uterus. Appropriate precautions are taken to minimize this risk.
It’s important to discuss any concerns or questions you may have about the risks and potential complications with your doctor before undergoing the procedure.
Also, Read- Endometrial Cancer Risk Factors
Interpreting the Results
Once the tissue sample is collected, it will be sent to a laboratory for analysis. A pathologist will examine the sample under a microscope and provide a detailed report to your gynecologist or oncologist.
The results will help determine if any abnormalities or conditions are present in the endometrium.
Your endometrial cancer surgeon in Mumbai will discuss the results with you and explain their implications. It’s important to remember that abnormal results do not necessarily indicate cancer.
Further testing or treatment may be necessary depending on the results.
It is important to follow up with a physician after a biopsy to discuss any changes in symptoms that may have occurred since the procedure, as well as the results of the biopsy.
This follow-up appointment will provide an opportunity for open dialogue and ensure proper diagnosis and treatment.
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