Gallbladder cancer is a relatively rare form of cancer, accounting for only around 2% of all cancers. It can be deadly if not treated properly. It is a severe disease, and patients need to have accurate information.

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This blog will provide a comprehensive guide to gallbladder cancer, including its symptoms, diagnosis methods, and treatment options.

We hope that this information will help patients better understand their disease and make informed decisions about their care.

What is gallbladder cancer?

Gallbladder Cancer

The gallbladder is a small, pear-shaped organ that sits just below the liver. It stores bile, a digestive fluid produced by the liver. Bile helps to break down fats in the food we eat.

Gallbladder cancer occurs when cells in the gallbladder begin to grow out of control. These cancerous cells can spread (metastasize) to other body parts, such as the liver or pancreas.

Gallbladder cancer is more common in some populations than others. For example, it is more common in Native Americans and Asians than in other groups.

What are the symptoms of gallbladder cancer?

The symptoms of gallbladder cancer can be hard to detect in the early stages of the disease. Many people with gallbladder cancer do not have any symptoms until the cancer has grown large enough to press on nearby organs or block the bile ducts.

When symptoms do occur, they may include:

  • Jaundice (yellowing of the skin and eyes)
  • Abdominal pain or bloating
  • Nausea and vomiting
  • Loss of appetite
  • Weight loss
  • Fatigue

Other conditions, such as gallstones or pancreatitis can also cause these symptoms. If you experience any of these symptoms, it’s important to see your doctor for a proper diagnosis.

How is gallbladder cancer diagnosed?

Gallbladder cancer is typically first discovered when a person experiences symptoms. These symptoms can include abdominal pain, jaundice, and weight loss.

If your doctor suspects you may have gallbladder cancer, they will likely order one or more of the following tests:

  • Imaging tests: Imaging tests, such as an ultrasound, CT scan, or MRI, can help to assess the size and location of a tumor.
  • Biopsy: A biopsy is the removal of a small sample of tissue for examination under a microscope. This is the only way to diagnose gallbladder cancer definitively.
  • Blood tests: Blood tests, such as a complete blood count or liver function test, can help to assess your general health and check for signs of liver damage.

Your doctor may also order other tests to rule out conditions that can cause similar symptoms.

What are the different types of gallbladder cancer?

Gallbladder cancer can be classified into two main types:

  • Adenocarcinoma: This is the most common type of gallbladder cancer, accounting for about 80% of all cases.
  • Cholangiocarcinoma: This type of cancer starts in the bile ducts and accounts for about 20% of all cases.

Stages of gallbladder cancer

There are three main stages of gallbladder cancer:

  • Stage 0: The cancer is confined to the lining of the gallbladder.
  • Stage I: Cancer has spread through the gallbladder wall into nearby tissues.
  • Stage II: Cancer has spread to nearby lymph nodes.
  • Stage III: Cancer has spread to other body parts, such as the liver or pancreas.
  • Stage IV: Cancer has spread to distant body parts, such as the lungs or bones.

What are the treatment options for gallbladder cancer?

The treatment options for gallbladder cancer depend on the stage of the disease. Treatment typically includes surgery to remove the cancerous tumor and chemotherapy or radiation therapy to kill any remaining cancer cells.

If the cancer is caught in the early stages, surgery may be all that is needed. However, if cancer has spread to other parts of the body, more aggressive treatment may be necessary.

Chemotherapy and radiation therapy are often combined with surgery to treat gallbladder cancer. These treatments can help to kill cancer cells that remain after surgery.

Targeted therapy is a newer type of treatment that uses drugs to target specific mutations in cancer cells. This type of therapy is sometimes used to treat gallbladder cancer that has spread to other parts of the body and is not responding to other treatments.

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Side effects of gallbladder cancer treatment

The side effects of gallbladder cancer treatment depend on the type and intensity of the treatment. Surgery, chemotherapy, and radiation therapy can all cause side effects.

Possible side effects of surgery include pain, bleeding, and infection. Chemotherapy and radiation therapy can cause a wide range of side effects, including nausea, vomiting, fatigue, and hair loss.

Some side effects may go away on their own or can be treated with medication. However, other side effects may be more severe and require medical attention.

Be sure to discuss the potential side effects of your treatment with your doctor before starting any treatment. This will help you to be prepared for what to expect during and after treatment.

What can you do to prevent gallbladder cancer?

There is no sure way to prevent gallbladder cancer. However, there are some things you can do to lower your risk, such as:

  • Eating a healthy diet: A diet high in fresh fruits and vegetables and low in saturated and trans fats may help to lower your risk of gallbladder cancer.
  • Maintaining a healthy weight: Being overweight or obese can increase your risk of gallbladder cancer. Maintaining a healthy weight may help to lower your risk.
  • Exercising regularly: Getting regular exercise can also help to reduce your risk of gallbladder cancer.
  • Avoiding certain infections: Some infections, such as the Helicobacter pylori bacteria, have increased gallbladder cancer risk. Avoiding these infections may help to lower your risk.

If you are at high risk for gallbladder cancer, your doctor may recommend regular screening tests to help catch the disease in its early stages. These tests may include imaging tests or blood tests.

What is the prognosis for gallbladder cancer?

The prognosis for gallbladder cancer depends on the stage of the disease. In general, the earlier the cancer is caught, the better the chances for a successful recovery.

Stage 0 and stage I gallbladder cancers have a five-year survival rate of around 80%. However, survival rates drop to around 10% for stage IV gallbladder cancer.

It’s important to remember that these are only averages. Your prognosis will depend on your unique situation. Be sure to discuss your prognosis with your doctor.

Coping with the emotional impact of gallbladder cancer

A diagnosis of cancer can be emotionally devastating. You may feel scared, confused, and alone.

It’s important to remember that you are not alone. There are many resources available to help you through this difficult time.

Consider talking to a counselor or joining a support group. These resources can help you to cope with the emotional impact of cancer.


The outcomes for the treatment of gallbladder cancer depends on the stage. Early-stage cancer has much better outcomes than advanced-stage cancer. In addition, it’s essential to take care of yourself during treatment.

Get plenty of rest and exercise, eat a healthy diet, and avoid alcohol. Taking care of yourself will help you stay strong and better able to fight cancer.

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